ANTIBACTERIAL EFFICACY OF Anopheles gambiae (MOSQUITOES) EXTRACTS ON SOME BACTERIA CAUSING THROAT INFECTIONS

Introduction: Respiratory tract infection refers to any infectious disease involving the respiratory tract. In low-income and middle-income countries, is considered as one of major public health problems. It can lead severe mortality morbidity in children well adults. Over years there has been a development resistance antibiotics used for treatment throat infections which led search alternative therapy. Insects be potentially useful an therapy because diverse bioactive compounds they possess. Objective: This research investigated antibacterial activity extract Anopheles gambiae against bacterial isolates associated with infection. Methods: The insects were bred microbiology laboratory identified Department Biology, Federal University Technology, Akure. mosquitoes collect immobilized freezer at -4oC. extracts prepared by mecrating into 30% Dimethlsulfoxide (DMSO) its homogenization. Extracts then tested in-vitro using agar diffusion method. Results: method showed S. pyogenes (22.00 ± 0.58b mm), aureus (19.67 1.20mm) K. pneumoniae (24 1.15mm), while it no E. coli pneumoniae. Conclusion: A. may medicine combat issue increasing multidrug conventional antibiotics, side effects these high cost synthetic drugs production. most prevalent compound was n-hexadecenoic retention time 20.997, reported exhibit antioxidant antimicrobial activity.